Article
HER-2 amplification but not butyrylcholinesterase multability reflects aggressiveness of European-originated ovarian tumors.
Gynecologic oncology - 1 Feb 1995
Dobianer K, Hruza C, Ehrlich G, Sevelda P, Czerwenka K, Soreq H, Spona J, Zakut H
Abstract excerpt
Tumorigenic roles were variably suggested for HER-2 and INT-2 oncogene amplifications and the "atypical" aspartate to glycine mutability in the butyrylcholinesterase (BCHE) gene in ovarian adenocarcinomas. To examine this notion we searched for correlations between these three phenomena and ovari...
Topics
- Base Sequence
- Biopsy
- Butyrylcholinesterase
- Female
- Fibroblast Growth Factor 3
- Fibroblast Growth Factors
- Genes, erbB-2
- Humans
- Molecular Sequence Data
- Mutation
- Ovarian Neoplasms
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Prognosis
- Proto-Oncogene Proteins