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Article

Identification of the coexisting HER2 gene amplification and novel mutations in the HER2 protein-overexpressed mucinous epithelial ovarian cancer.

Annals of surgical oncology - 1 Aug 2011

Lin Wea-Lung, Kuo Wu-Hsien, Chen Fong-Lin, Lee Ming-Yung, Ruan Alexandra, Tyan Yeu-Sheng, Hsu Jeng-Dong, Chiang Hung, Han Chih-Ping

Abstract excerpt

BACKGROUND: Although overexpression, amplification, and somatic mutation of the HER2 gene have been noted in various types of human cancers, we report here for the first time that novel mutations and amplification of the HER2 gene occurred concomitantly in mucinous epithelial ovarian cancer (EOC). METHODS: Twenty-seven tissue microarray samples from EOC patients were analyzed by immunohistochemistry (IHC) with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 21347793
DOI: 10.1245/s10434-011-1572-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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