Article
An Escherichia coli strain deficient for both exonuclease V and deoxycytidine triphosphate deaminase shows enhanced sensitivity to ionizing radiation.
Molecular & general genetics : MGG - 20 Feb 1995
Estèvenon A M, Kooistra J, Sicard N
Abstract excerpt
An Escherichia coli mutant lacking deoxycytidine triphosphate deaminase (Dcd) activity and an unknown function encoded by a gene designated ior exhibits sensitivity to ionizing radiation whereas dcd mutants themselves are not sensitive. A DNA fragment from an E. coli genomic library that restores the wild type level of UV and gamma ray resistance to this mutant has been cloned in the multicopy vector pBR322....
Topics
- Chromosome Mapping
- Cloning, Molecular
- DNA Repair
- DNA, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Exodeoxyribonuclease V
- Exodeoxyribonucleases
- Mutation
- Nucleotide Deaminases