Article
Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria.
Blood - 15 Mar 1995
Ostendorf T, Nischan C, Schubert J, Grussenmeyer T, Scholz C, Zielinska-Skowronek M, Schmidt R E
Abstract excerpt
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal defect of hematopoietic stem cells in which affected cells are characterized by the lack of glycosylphosphatidylinositol (GPI)-anchored proteins. The lesion in PNH lies in the defective synthesis of N-acetyl-D-glucosaminyl-phosphatid...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Base Sequence
- Cell Line
- Glycosylphosphatidylinositols
- Hemoglobinuria, Paroxysmal
- Humans
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction