Article
Genetic stability of rDNA production systems, a case report.
Developments in biological standardization - 1 Jan 1994
Chiu Y Y
Abstract excerpt
Producing rDNA proteins to be used as human therapeutic agents requires a biological production system during both storage and growth. The genetic make-up of a biological system is usually known through the laboratory history of the host strain and the process of vector construction. All master cell banks prepared for the production of medicinal products are fully characterized at the genetic and biochemical...
Topics
- Biotechnology
- DNA, Recombinant
- Escherichia coli
- Fermentation
- Genetic Vectors
- Humans
- Mutation
- Plasmids
- Quality Control
- Recombinant Proteins
- Saccharomyces cerevisiae