Environmentally-regulated genes of hypertension.

Abstract excerpt

Several monogenetic causes of hypertension have recently been identified, but for the most part, the disease is of polygenic and possibly heterogenous character. The environmental impact, representing about 2/3 of blood pressure variance, is usually thought to be exerted at the level of phenotypic modification, additive to the effect of genetic loci determining blood pressure. The concept presented here is that...

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