Article
Evaluation of LEXF/FXLE rat recombinant inbred strains for genetic dissection of complex traits.
Physiological genomics - 19 Feb 2008
Voigt Birger, Kuramoto Takashi, Mashimo Tomoji, Tsurumi Toshiko, Sasaki Yoshiyuki, Hokao Ryoji, Serikawa Tadao
Abstract excerpt
Recombinant inbred (RI) strains are formed from an outcross between two well-characterized inbred stains followed by at least 20 generations of inbreeding. RI strains can be utilized for the analysis of many complex phenotypic traits. The LEXF/FXLE RI strain set consists of 34 RI strains derived by reciprocal crossing of LE/Stm and F344/Stm. Here we report on genetic dissections of complex traits using this RI...
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