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Article

Mutations in the structural gene for cytochrome c result in deficiency of both cytochromes aa3 and c in Neurospora crassa.

Current genetics - 1 Oct 1994

Bottorff D A, Parmaksizoglu S, Lemire E G, Coffin J W, Bertrand H, Nargang F E

Abstract excerpt

The cyt-12-12 mutant of Neurospora crassa is characterized by slow growth and a deficiency of spectrophotometrically-detectable cytochromes aa3 and c. Using a sib-selection procedure we have isolated the cyt-12+ allele from a cosmid library of N. crassa genomic DNA. Characterization of the cyt-12+ allele reveals that it encodes the structural gene for cytochrome c. DNA sequence analysis of the cyt-12-12 allele...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Cytochrome c Group
DNA, Fungal
Electron Transport Complex IV
Genes, Fungal
Humans
Mitochondria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Neurospora crassa

Phenotype

Sequence Homology, Amino Acid

Source

Identifiers

PMID: 7882427
DOI: 10.1007/BF00310497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7882427-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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