Article
Is there an inverse relationship between Down's syndrome and bipolar affective disorder? Literature review and genetic implications.
Journal of intellectual disability research : JIDR - 1 Dec 1994
Craddock N, Owen M
Abstract excerpt
Several authors have suggested the existence of an inverse relationship between bipolar affective disorder and Down's syndrome (DS). The present authors have examined this hypothesis by a critical review of the literature. The present findings are consistent with a reduced rate of bipolar disorde...
Topics
- Alleles
- Bipolar Disorder
- Chromosomes, Human, Pair 21
- Down Syndrome
- Genes, Dominant
- Genes, Recessive
- Humans
- Risk Factors