Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans.

doi:10.1006/jmbi.1994.0102

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Beta-tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans.

Journal of molecular biology - 3 Mar 1995

Kwa M S, Veenstra J G, Van Dijk M, Roos M H

Abstract excerpt

Resistance to antimitotic chemotherapeutics in pathogenic nematodes, fungi and mammalian cells is closely associated with structural changes in cytoskeletal beta-tubulin. We investigated the possibility of using the well-characterised free-living nematode Caenorhabditis elegans as a model for stu...

Topics

Amino Acid Sequence
Animals
Antinematodal Agents
Base Sequence
Caenorhabditis elegans
Drug Resistance
Haemonchus
Helminth Proteins
Molecular Sequence Data
Mutation
Structure-Activity Relationship
Transformation, Genetic
Tubulin

Source

Open in PubMed

Identifiers

PMID: 7877171
DOI: 10.1006/jmbi.1994.0102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7877171-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics