Identification of three distinct allelic forms of bovine CD4.

Abstract excerpt

The CD4-specific monoclonal antibody (mAb) CC26, when tested on a total of 143 cattle, failed to react with T cells from 16% of animals and gave reduced intensity staining in a further 35% of animals. The results of family studies with groups of half- and full-siblings indicated that CC26 recognizes an allele of CD4 which is co-dominantly expressed in heterozygous animals. This was confirmed by sequential...

Topics

• Alleles
• Animals
• Antibodies, Monoclonal
• Antibody Specificity
• CD4 Antigens
• CD4-Positive T-Lymphocytes
• Cattle
• Female
• Glycosylation
• Leukocytes, Mononuclear
• Male
• Molecular Weight