Genetic control of susceptibility to leprosy in French Polynesia; no evidence for linkage with markers on telomeric human chromosome 2.

Article

Genetic control of susceptibility to leprosy in French Polynesia; no evidence for linkage with markers on telomeric human chromosome 2.

International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association - 1 Dec 1994

Levee G, Liu J, Gicquel B, Chanteau S, Schurr E

Abstract excerpt

Several lines of evidence have suggested a role of genetic factors in susceptibility to leprosy. In the mouse, natural susceptibility to infection with mycobacteria is controlled by the chromosome 1 Bcg locus, a region which is syntenic with a fragment of the human chromosome 2q, region q31-q37. It has been postulated that a human homolog of the Bcg gene controls susceptibility to leprosy per se, and may be...

Topics

Chromosomes, Human, Pair 2
Female
Genes, Recessive
Genetic Markers
Genetic Predisposition to Disease
Humans
Leprosy
Lod Score
Male
Pedigree

Polynesia

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