Article
Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q.
Diabetes - 1 Feb 1995
Doria A, Caldwell J S, Ji L, Reynet C, Rich S S, Weremowicz S, Morton C C, Warram J H, Kahn C R, Krolewski A S
Abstract excerpt
A 10-allele polymorphism was identified in rad (ras associated with diabetes), a gene that is overexpressed in non-insulin-dependent diabetes mellitus (NIDDM) muscle. The polymorphism, designated RAD1, consists of a variable number of trinucleotide repeats (GTT and ATT) located in the poly(A) reg...
Topics
- Alleles
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 16
- Diabetes Mellitus, Type 2
- Genes, ras
- Genotype
- Humans
- In Situ Hybridization, Fluorescence
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
- Repetitive Sequences, Nucleic Acid
