Article
Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q.
Diabetes - 1 Feb 1995
Doria A, Caldwell J S, Ji L, Reynet C, Rich S S, Weremowicz S, Morton C C, Warram J H, Kahn C R, Krolewski A S
Abstract excerpt
A 10-allele polymorphism was identified in rad (ras associated with diabetes), a gene that is overexpressed in non-insulin-dependent diabetes mellitus (NIDDM) muscle. The polymorphism, designated RAD1, consists of a variable number of trinucleotide repeats (GTT and ATT) located in the poly(A) region of an intronic Alu sequence. Based on the number of GTT and ATT repetitions, the alleles can be grouped into four...
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