Article
Usefulness of dinucleotide polymorphism markers in genetic analysis of Duchenne's muscular dystrophy cases in Singapore.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 1995
Lai P S, Chiu L L, Low P S, Lee W L, Tay J S
Abstract excerpt
Dinucleotide polymorphisms are short tandem repeat sequences that can be used as probes for haplotype analysis in Duchenne's muscular dystrophy (DMD). There are approximately a total of 50,000 to 100,000 such loci in the human genome, and they are highly informative due to the variability of alle...
Topics
- Alleles
- DNA
- Dystrophin
- Female
- Genetic Markers
- Haplotypes
- Humans
- Introns
- Lymphocytes
- Male
- Muscular Dystrophies
- Pedigree
- Polymerase Chain Reaction
