Vitamin-D-receptor-gene polymorphisms and change in lumbar-spine bone mineral density.

doi:10.1016/s0140-6736(95)90404-2

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Article

Vitamin-D-receptor-gene polymorphisms and change in lumbar-spine bone mineral density.

Lancet (London, England) - 18 Feb 1995

Ferrari S, Rizzoli R, Chevalley T, Slosman D, Eisman J A, Bonjour J P

Abstract excerpt

Common vitamin-D-receptor (VDR) gene allelic variants predict bone mineral density. We analysed VDR alleles and rate of change of lumbar-spine bone mineral density over 18 months in 72 elderly subjects. 9 BB homozygotes lost bone mineral density but 26 homozygotes for the alternative genotype (bb...

Topics

Aged
Bone Density
Cohort Studies
Female
Genotype
Humans
Lumbar Vertebrae
Male
Osteoporosis
Polymorphism, Genetic
Receptors, Calcitriol

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