Article
Substitution processes in molecular evolution. III. Deleterious alleles.
Genetics - 1 Nov 1994
Gillespie J H
Abstract excerpt
The substitution processes for various models of deleterious alleles are examined using computer simulations and mathematical analyses. Most of the work focuses on the house-of-cards model, which is a popular model of deleterious allele evolution. The rate of substitution is shown to be a concave...
Topics
- Alleles
- Biological Evolution
- Computer Simulation
- Models, Genetic