Article
Deleterious passengers in adapting populations.
Genetics - 1 Nov 2014
Good Benjamin H, Desai Michael M
Abstract excerpt
Most new mutations are deleterious and are eventually eliminated by natural selection. But in an adapting population, the rapid amplification of beneficial mutations can hinder the removal of deleterious variants in nearby regions of the genome, altering the patterns of sequence evolution. Here,...
Topics
- Adaptation, Biological
- Biological Evolution
- Genetic Fitness
- Models, Genetic
- Mutation