Article
[Detection of methicillin-resistant Staphylococcus aureus using PCR and non-radioactive DNA probes: IV. Mutational sequences in the region upstream of the mec A gene in clinical staphylococcal strains].
Rinsho byori. The Japanese journal of clinical pathology - 1 Nov 1994
Yamashita K, Takarada Y, Muto T, Otsuka N, Kagawa S, Matsuoka A
Abstract excerpt
Expression of mec A is regulated by two regulatory genes (mecR1 and mecI); the intact regulatory genes exist in the N315 strain of methicillin-sensitive S. aureus, whereas the repressor gene (mecI) is deleted in the MR108 strain of methicillin-resistant S. aureus (MRSA). However, our previous fin...
Topics
- Base Sequence
- DNA Probes
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Methicillin Resistance
- Molecular Sequence Data
- Mutation
- Operator Regions, Genetic
- Polymerase Chain Reaction
- Sequence Analysis