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Article

The I Domain is Essential for Echovirus 1 Interaction with VLA-2

1 Jan 1994

Abstract excerpt

VLA-2, the alpha 2 beta 1 integrin, mediates cell adhesion to collagen and laminin, and is the receptor for the human pathogen echovirus 1. Because of its similarity to domains present in other proteins that interact with collagen, a 191 amino acid region within the alpha 2 subunit (the I domain) has been proposed as a potential site for ligand interactions. Although the alpha 2 subunits of human and murine VLA-2...

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PMID: 7842258
DOI: 10.3109/15419069409004455

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