Article
gyrA mutations in quinolone-resistant isolates of the fish pathogen Aeromonas salmonicida.
Antimicrobial agents and chemotherapy - 1 Oct 1994
Oppegaard H, Sørum H
Abstract excerpt
gyrA mutations in quinolone-resistant isolates of Aeromonas salmonicida have been detected by using PCR to amplify the quinolone resistance-determining region of gyrA and subsequent cloning and sequencing of PCR products. Comparison of nucleotide and derived amino acid sequences of PCR products from quinolone-susceptible and -resistant bacteria revealed a serine 83-to-isoleucine substitution in the gyrase A...
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