Article
Detection of S83V GyrA mutation in quinolone-resistant Shewanella algae using comparative genomics.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Aug 2021
Tseng Chien-Hao, Cheng Jan-Fang, Chen Shi-Yu, Chen Wen-Huei, Shi Zhi-Yuan, Lin Yu-Hui, Tsai Che-An, Lin Shih-Ping, Chen Yung-Chun, Lin Yu-Chia, Huang Yao-Ting, Liu Po-Yu
Abstract excerpt
BACKGROUND: Shewanella algae is a zoonotic pathogen that poses a serious health threat to immunocompromised hosts. Treatment of S. algae infections is challenging due to the pathogen's intrinsic resistance to a variety of β-lactam antibiotics. Therapeutic options have become further limited by the emergence of quinolone-resistant strains. Currently, there are few studies concerning the genetic and molecular...
Topics
- Anti-Bacterial Agents
- DNA Gyrase
- Drug Resistance, Bacterial
- Genomics
- Gram-Negative Bacterial Infections
- Humans
- Microbial Sensitivity Tests
- Mutation
- Quinolones
- Shewanella
- Whole Genome Sequencing