Article
Pathogenetic Potential Relating to Metabolic Activity in a Mouse Model of Infection with the Chikungunya Virus East/Central/South African Genotype.
Viruses - 3 Feb 2020
Ngwe Tun Mya Myat, Muthugala Rohitha, Kyaw Kyaw Aung, Shimada Satoshi, Morita Kouichi, Hayasaka Daisuke
Abstract excerpt
Epidemics of the Chikungunya virus (CHIKV) from 2004 onwards were caused by the East/Central/South African (ECSA) genotype. However, the pathogenesis of the genotype infection has not been fully explained. In this study, we examined the pathogenic potential of CHIKV ECSA genotype M-30 (M-30) by comparing it with that of African genotype S-27 (S-27) in mice. Following low titer infections in type-I IFN receptor KO...
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