Article
Human immunodeficiency virus type 1 Rev- and Tat-specific cytotoxic T lymphocyte frequencies inversely correlate with rapid progression to AIDS.
The Journal of general virology - 1 Aug 1997
van Baalen C A, Pontesilli O, Huisman R C, Geretti A M, Klein M R, de Wolf F, Miedema F, Gruters R A, Osterhaus A D
Abstract excerpt
Immunological correlates of AIDS-free survival after human immunodeficiency virus type 1 (HIV-1) infection are largely unknown. Cytotoxic T lymphocyte (CTL) responses are generally believed to be a major component of protective immunity against viral infections. However, the relationship between...
Topics
- Acquired Immunodeficiency Syndrome
- Alleles
- Amino Acid Sequence
- CD4 Lymphocyte Count
- DNA Primers
- Disease Progression
- Follow-Up Studies
- Gene Products, rev
- Gene Products, tat
- HIV Seropositivity
- HIV-1
- HLA-A Antigens
- HLA-A1 Antigen
- HLA-A2 Antigen