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Early Levels of HIV‐1 DNA in Peripheral Blood Mononuclear Cells Are Predictive of Disease Progression Independently of HIV‐1 RNA Levels and CD4+T Cell Counts

6 Jun 2005

Abstract excerpt

BACKGROUND: The objective of this work was to assess the role of human immunodeficiency virus (HIV) reservoirs in the risk of disease progression, by studying the relationship between HIV DNA level in peripheral blood mononuclear cells (PBMCs) and progression toward acquired immunodeficiency syndrome (AIDS). METHODS: HIV-1 DNA levels in PBMCs were determined by quantitative polymerase chain reaction for 383...

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PMID: 15942893
DOI: 10.1086/430610

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