Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Local and Global Structural Properties of the HIV-MN V3 Loop

1 Feb 1995

Abstract excerpt

Studies of the feasibility of a subunit vaccine to protect against human immunodeficiency virus (HIV) infection have principally focused on the third variable (V3) loop. The principal neutralizing determinant (PND) of HIV-1 is located inside the V3 loop of the surface envelope glycoprotein, gp120. However, progress toward a PND-based vaccine has been impeded by the amino acid sequence variability in the V3 loops...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to Monoclonal and Polyclonal Antibodies Research
Share to Protein Structure and Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7836454
DOI: 10.1074/jbc.270.5.2224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Local and Global Structural Properties of the HIV-MN V3 LoopPMID 7836454Read ↗

Recognition properties of V3-specific antibodies to V3 loop peptides derived from HIV-1 gp120 presented in multiple conformations.Semantic proximity Read ↗

Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.Semantic proximity Read ↗

HIV-1 gp120 V3 Loop for Structure-Based Drug DesignSemantic proximity Read ↗

Structure of a V3-Containing HIV-1 gp120 CoreSemantic proximity Read ↗

Structural analysis of the envelope gp120 V3 loop for some HIV-1 variants circulating in the countries of Eastern Europe.Semantic proximity Read ↗

Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization SensitivitySemantic proximity Read ↗

Sequence variation and consensus sequence of V3 loop on HIV-1 gp120.Semantic proximity Read ↗

An optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120Semantic proximity Read ↗

Diversity of the V3 region of HIV in Paris, France.Semantic proximity Read ↗

Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.Semantic proximity Read ↗

Selective modification of variable loops alters tropism and enhances immunogenicity of human immunodeficiency virus type 1 envelope.Semantic proximity Read ↗

Independent divergences in the CD4 binding site and V3 loop encoded in two seroprevalent Ugandan HIV-1 clinical isolates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.