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Article

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 Jan 1995

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7834749
DOI: 10.1016/0092-8674(95)90412-3

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Tumor suppressor p53 is a direct transcriptional activator of the human bax genePMID 7834749Read ↗

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genesSemantic proximity Read ↗

The Tumor Suppressor Protein p53 Requires a Cofactor to Activate Transcriptionally the Human BAX PromoterSemantic proximity Read ↗

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.Semantic proximity Read ↗

Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR elementSemantic proximity Read ↗

Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressorSemantic proximity Read ↗

Direct interaction of p53 with the Y-box binding protein,YB-1 : A mechanism for regulation of human gene expressionSemantic proximity Read ↗

Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expressionSemantic proximity Read ↗

Puma, a critical mediator of cell death — one decade on from its discoverySemantic proximity Read ↗

Inhibition of Bax activity is crucial for the antiapoptotic function of the human papillomavirus E6 oncoproteinSemantic proximity Read ↗

The apoptotic and transcriptional transactivation activities of p53 can be dissociated.Semantic proximity Read ↗

p73 is a human p53-related protein that can induce apoptosisSemantic proximity Read ↗

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family membersSemantic proximity Read ↗

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