Article
Biological and genetic changes in ovine lentivirus strains following passage in isogeneic twin lambs.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Feb 1995
Woodward T M, Carlson J O, de la Concha-Bermejillo A, DeMartini J C
Abstract excerpt
Ovine lentivirus (OvLV) strains vary in cytopathogenicity, but the correlation, if any, between viral cytophenotypes and in vivo pathogenicity is poorly understood. To examine this issue and to evaluate changes in OvLV strains following passage in vivo, biological and genetic characteristics of OvLV isolates following in vivo passage were compared with those of the parent strain used for inoculation of two sets...
Topics
- Animals
- Base Sequence
- Cytopathogenic Effect, Viral
- Genes, env
- Genetic Variation
- Molecular Sequence Data
- Pneumonia, Progressive Interstitial, of Sheep
- Serial Passage
- Sheep
- Twin Studies as Topic