Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Permissiveness of different TMEM154 genotype cell lines to different SRLV genotypes/subtypes.

Journal of virology - 23 Sept 2025

Colitti Barbara, Avanzato Daniele, Moretti Riccardo, Moncayola Irati, Profiti Margherita, Chessa Stefania, Sacchi Paola, Rosati Sergio, Reina Ramses

Abstract excerpt

Small ruminant lentiviruses (SRLVs) are a heterogeneous group of viruses that infect goats and sheep worldwide, for which no cures or effective vaccines are available. Control measures have been based on early diagnosis and accurate management with limited success due to re-emergence of seropositivity and disease in controlled flocks. Association between the genetic variation in the ovine transmembrane 154...

Topics

Animals
Sheep
Genotype
Cell Line
Goats
Membrane Proteins
Lentivirus Infections
Sheep Diseases
Polymorphism, Single Nucleotide
Lentivirus
Goat Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Internalization

Fibroblasts

Source

Open in PubMed Open full text

Identifiers

PMID: 40844279
DOI: 10.1128/jvi.00961-25
PMCID: PMC12455981

Genes

TMEM154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Permissiveness of different TMEM154 genotype cell lines to different SRLV genotypes/subtypes.PMID 40844279Read ↗

Genetic subgroup of small ruminant lentiviruses that infects sheep homozygous for TMEM154 frameshift deletion mutation A4Δ53.Semantic proximity Read ↗

Susceptibility of different TMEM154 genotypes in three Italian sheep breeds infected by different SRLV genotypes.Semantic proximity Read ↗

Small ruminant lentivirus genetic subgroups associate with sheep TMEM154 genotypes.Semantic proximity Read ↗

Progress on ovine lentivirus and its resistant genes.Semantic proximity Read ↗

First Survey of SNPs in TMEM154, TLR9, MYD88 and CCR5 Genes in Sheep Reared in Italy and Their Association with Resistance to SRLVs Infection.Semantic proximity Read ↗

First survey on association of TMEM154 and CCR5 variants with serological maedi-visna status of sheep in German flocks.Semantic proximity Read ↗

Mutations in Ovis aries TMEM154 are associated with lower small ruminant lentivirus proviral concentration in one sheep flock.Semantic proximity Read ↗

Genetic testing for TMEM154 mutations associated with lentivirus susceptibility in sheep.Semantic proximity Read ↗

Lentivirus Susceptibility in Brazilian and US Sheep with TMEM154 Mutations.Semantic proximity Read ↗

Small ruminant lentiviruses: genetic variability, tropism and diagnosis.Semantic proximity Read ↗

Reduced lentivirus susceptibility in sheep with TMEM154 mutations.Semantic proximity Read ↗

Effects of TMEM154 haplotypes 1 and 3 on susceptibility to ovine progressive pneumonia virus following natural exposure in sheep.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.