Article
Rh E/e genotyping by allele-specific primer amplification.
Blood - 1 Feb 1995
Faas B H, Simsek S, Bleeker P M, Overbeeke M A, Cuijpers H T, von dem Borne A E, van der Schoot C E
Abstract excerpt
It has been shown that the Rhesus (Rh) blood group antigens are encoded by two homologous genes: the Rh D gene and the Rh CcEe gene. The Rh CcEe gene encodes different peptides: the Rh C, c, E, and e polypeptides. Only one nucleotide difference has been found between the alleles encoding the Rh E and the Rh e antigen polypeptides. It is a C-->G transition at nucleotide position 676, which leads to an amino acid...
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