Article
A southern analysis of Rh blood group genes: association between restriction fragment length polymorphism patterns and Rh serotypes.
Blood - 15 Jan 1994
Hyland C A, Wolter L C, Liew Y W, Saul A
Abstract excerpt
Polymorphisms within the Rh blood group system have been defined by serologic agglutination methods, but have not yet been defined at the DNA level. Two closely related genes associated with the Rh D antigen and with the Rh C/c and E/e antigens have been cloned. We used a Southern analysis incorporating probes to the 5' and 3' regions of the Rh C, E gene and D gene to identify polymorphisms associated with Rh C/c...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- Humans
- Molecular Sequence Data
- Phenotype
- Polymorphism, Restriction Fragment Length
- Rh-Hr Blood-Group System