Article
Molecular basis of the RhCW (Rh8) and RhCX (Rh9) blood group specificities.
Blood - 1 Aug 1995
Mouro I, Colin Y, Sistonen P, Le Pennec P Y, Cartron J P, Le Van Kim C
Abstract excerpt
The Rh blood group antigens are encoded by two highly related genes, RHD and RHCE, and the sequence of the common alleles (D, Ce, CE, ce, and cE) of these genes has been previously elucidated. In this report, Rh transcripts and gene fragments have been amplified using polymerase chain reaction from the blood of donors with the CW+ andCX+ phenotypes. Sequence analysis indicated that the expression of the CW (Rh8)...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA Primers
- Humans
- Membrane Proteins
- Molecular Sequence Data
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Rh-Hr Blood-Group System
