RHD/CE typing by polymerase chain reaction using sequence-specific primers.

doi:10.1046/j.1537-2995.1997.371098016439.x

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Article

RHD/CE typing by polymerase chain reaction using sequence-specific primers.

Transfusion - 1 Oct 1997

Gassner C, Schmarda A, Kilga-Nogler S, Jenny-Feldkircher B, Rainer E, Müller T H, Wagner F F, Flegel W A, Schönitzer D

Abstract excerpt

BACKGROUND: Current DNA-based Rh system typing strategies may detect the two RH genes and their prevalent alleles, but they are known to fail sometimes, when rare RH alleles (e.g., D category phenotypes) are encountered. It is almost impossible to find a single DNA-based method that can accommoda...

Topics

Blood Donors
Blood Grouping and Crossmatching
DNA Primers
Epitopes
Exons
Gene Frequency
Genes
Genetic Variation
Humans
Polymerase Chain Reaction
Rh-Hr Blood-Group System

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