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Article

Cleaved antithrombin (ATc): a new marker for thrombin generation and activation of the coagulation system.

British journal of haematology - 1 Jan 1995

Lindo V S, Kakkar V V, Melissari E

Abstract excerpt

A modified form of antithrombin (AT) cleaved at the active site by thrombin (ATc) has been shown to be generated in vivo, corresponding to 1-4% of the circulating AT. An enzyme immunoassay has been developed for measuring ATc following plasma treatment with ammonium sulphate and heat denaturation of native AT. ATc plasma levels were found to be significantly higher (P = 0.003) in patients developing venous...

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Identifiers

PMID: 7833256
DOI: 10.1111/j.1365-2141.1995.tb08923.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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