Article
Cell-type-specific regulation of the two foamy virus promoters.
Journal of virology - 1 Jul 2001
Meiering C D, Rubio C, May C, Linial M L
Abstract excerpt
The foamy virus (FV) genome contains two promoters, the canonical long terminal repeat (LTR) promoter, containing three consensus AP-1 binding sites, and an internal promoter (IP) within the env gene. We investigated the regulation of the two promoters in lytic and persistent infections and found that in the presence of a constitutive source of the viral transactivator protein Tas, transactivation of the LTR...
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