Article
A family history study of schizophrenia spectrum disorders suggests new candidate genes in schizophrenia and autism.
The Psychiatric quarterly - 1 Jan 1994
Goodman A B
Abstract excerpt
To limit genetic heterogeneity, this study focused on the widely extended pedigrees of Ashkenazi Jewish schizophrenic and autistic probands, to determine if similar causal mechanisms might obtain for both conditions. At least two previous epidemiological studies have demonstrated increased risk for schizophrenia in Ashkenazi Jews. The hypothesis posed is that increased prevalence of various rare autosomal...
Topics
- Adult
- Amyotrophic Lateral Sclerosis
- Autistic Disorder
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 21
- Female
- Gaucher Disease
- Gene Pool
- Humans
- Jews
- Male
- Middle Aged