Article
Multiple glucose 6-phosphate dehydrogenase-deficient variants correlate with malaria endemicity in the Vanuatu archipelago (southwestern Pacific).
American journal of human genetics - 1 Jan 1995
Ganczakowski M, Town M, Bowden D K, Vulliamy T J, Kaneko A, Clegg J B, Weatherall D J, Luzzatto L
Abstract excerpt
In studying the relationship between genetic abnormalities of red blood cells and malaria endemicity in the Vanuatu archipelago in the southwestern Pacific, we have found that of 1,442 males tested, 98 (6.8%) were G6PD deficient. The prevalence of GdPD deficiency varied widely (0%-39%), both from...
Topics
- Adolescent
- Adult
- Anemia, Hemolytic
- Base Sequence
- Child
- Child, Preschool
- Cluster Analysis
- DNA Mutational Analysis
- Female
- Genetic Predisposition to Disease
- Glucosephosphate Dehydrogenase
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Infant