Article
G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon.
Malaria journal - 15 Jun 2017
Dombrowski Jamille G, Souza Rodrigo M, Curry Jonathan, Hinton Laura, Silva Natercia R M, Grignard Lynn, Gonçalves Ligia A, Gomes Ana Rita, Epiphanio Sabrina, Drakeley Chris, Huggett Jim, Clark Taane G, Campino Susana, Marinho Claudio R F
Abstract excerpt
BACKGROUND: Plasmodium vivax parasites are the predominant cause of malaria infections in the Brazilian Amazon. Infected individuals are treated with primaquine, which can induce haemolytic anaemia in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals and may lead to severe and fatal complications. This X-linked disorder is distributed globally and is caused by allelic variants with a geographical...
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