Article
Prevalence of Glucose 6-Phosphate Dehydrogenase Variants in Malaria-Endemic Areas of South Central Timor, Eastern Indonesia.
The American journal of tropical medicine and hygiene - 1 Aug 2020
Sulistyaningrum Novi, Arlinda Dona, Hutagalung Jontari, Sunarno Sunarno, Oktoberia Intan Sari, Handayani Sarwo, Ekowatiningsih Riyanti, Yusnita Endah Ariyanti, Prasetyorini Budi, Rizki Aulia, Tjitra Emiliana, Na-Bangchang Kesara, Chaijaroenkul Wanna
Abstract excerpt
Primaquine is an effective anti-hypnozoite drug for Plasmodium vivax and Plasmodium ovale. However, it can trigger erythrocyte hemolysis in people with glucose 6-phosphate dehydrogenase (G6PD) deficiency. In a previous report from South Central Timor (SCT), Indonesia, we described the prevalence of Vanua Lava, Chatham, and Viangchan variants; in this study, other G6PD variants (Kaiping, Coimbra, Gaohe, Canton,...
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