[What do we know about pathogenesis of psoriasis?].

Abstract excerpt

Psoriasis has been considered as a disease of the keratinocytes, or an autoimmune disease. According to the current view, altered interaction of the immune system with epithelial cells and mediators of the skin is essential in psoriasis. In genetically predisposed subjects, psoriasis may appear as a result of external factors, but no antigen or autoantigen triggering the inflammation has been identified. Genetic...

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