Article
The genetics of psoriasis and autoimmunity.
Annual review of genomics and human genetics - 1 Jan 2005
Bowcock Anne M
Abstract excerpt
Psoriasis is an inflammatory/autoimmune disease and, as with many autoimmune diseases, is associated with alleles from the major histocompatibility complex (MHC). With psoriasis and autoimmune disease, the penetrance of the MHC-associated alleles is never 100%, even for monozygotic twins. This may be because development requires additional environmental and/or genetic modifiers or requires specific T-cell...
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