Article
Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparum.
Infection and immunity - 1 Feb 1995
Egan A F, Chappel J A, Burghaus P A, Morris J S, McBride J S, Holder A A, Kaslow D C, Riley E M
Abstract excerpt
The major merozoite surface protein of Plasmodium falciparum (PfMSP1) is a candidate antigen for a malaria vaccine. A 19-kDa C-terminal processing product of PfMSP1 (PfMSP1(19)) is composed of two domains sharing a cysteine-rich motif with epidermal growth factor (EGF) and is the target of monocl...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Alleles
- Amino Acid Sequence
- Animals
- Antibodies, Protozoan
- Antigens, Protozoan
- Child
- Child, Preschool
- Consensus Sequence
- Cross Reactions
- Disulfides