Article
Resistance of a Tn4351-generated polysaccharide mutant of Porphyromonas gingivalis to polymorphonuclear leukocyte killing.
Infection and immunity - 1 Feb 1995
Genco C A, Schifferle R E, Njoroge T, Forng R Y, Cutler C W
Abstract excerpt
In this study, we describe the development of an efficient transpositional mutagenesis system for Porphyromonas gingivalis using the Bacteroides fragilis transposon Tn4351. Using this system, we have isolated and characterized a Tn4351-generated mutant of P. gingivalis A7436, designated MSM-1, wh...
Topics
- Antigens, Bacterial
- Cytotoxicity, Immunologic
- DNA Transposable Elements
- DNA, Bacterial
- Humans
- In Vitro Techniques
- Mutagenesis, Insertional
- Mutation
- Neutrophils
- Phagocytosis
- Polysaccharides, Bacterial
- Porphyromonas gingivalis
- Restriction Mapping
- Solubility