Article
Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene?
Lancet (London, England) - 14 Jan 1995
Levin M, Newport M J, D'Souza S, Kalabalikis P, Brown I N, Lenicker H M, Agius P V, Davies E G, Thrasher A, Klein N
Abstract excerpt
Inherited defects in specific components of the immune system have provided many clues to the immunological mechanisms underlying resistance to microbial infection. We report a familial immune defect predisposing to disseminated atypical mycobacterial infection in childhood. 6 children with disse...
Topics
- Adult
- Antigens, Bacterial
- Child
- Child, Preschool
- Chronic Disease
- Endotoxins
- Female
- Genetic Predisposition to Disease
- Humans
- Infant
- Interferon-gamma
- Lymphocyte Activation
- Male
- Mycobacterium Infections, Nontuberculous
- Nontuberculous Mycobacteria