Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

PloS one - 1 Jan 2014

Kotilainen Hannele, Lokki Marja-Liisa, Paakkanen Riitta, Seppänen Mikko, Tukiainen Pentti, Meri Seppo, Poussa Tuija, Eskola Jussi, Valtonen Ville, Järvinen Asko

Abstract excerpt

BACKGROUND: Non-tuberculous mycobacteria (NTM) are ubiquitous in the environment and they infect mainly persons with underlying pulmonary diseases but also previously healthy elderly women. Defects in host resistance that lead to pulmonary infections by NTM are relatively unknown. A few genetic defects have been associated with both pulmonary and disseminated mycobacterial infections. Rare disseminated NTM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement C4

Share to Disease Susceptibility

Share to Finland

Share to Mycobacterium Infections, Nontuberculous

Share to Nontuberculous Mycobacteria

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 24638111
DOI: 10.1371/journal.pone.0091450
PMCID: PMC3956671

Genes

NTM

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.PMID 24638111Read ↗

Host genetic factors and mycobacterial infections: lessons from single gene disorders affecting innate and adaptive immunity.Semantic proximity Read ↗

Host susceptibility to non-tuberculous mycobacterial infections.Semantic proximity Read ↗

Susceptibility to nontuberculous mycobacterial lung disease: Table 1—Semantic proximity Read ↗

Host genetic factors in susceptibility to mycobacterial disease.Semantic proximity Read ↗

Genetic, immunologic, and clinical features of 830 patients with Mendelian susceptibility to mycobacterial diseases (MSMD): A systematic review.Semantic proximity Read ↗

Acquired and genetic host susceptibility factors and microbial pathogenic factors that predispose to nontuberculous mycobacterial infectionsSemantic proximity Read ↗

GATA2 mutations in patients with non-tuberculous mycobacterial or fungal infections with unknown immunodeficiency in BrazilSemantic proximity Read ↗

C1q in non-immune human serum has a non-redundant complement function towards clinical Mycobacterium tuberculosis complex strainsSemantic proximity Read ↗

Pulmonary Nontuberculous Mycobacterial Infection. A Multisystem, Multigenic Disease.Semantic proximity Read ↗

Major histocompatibility complex class III (C2, C4, factor B) and C3 gene variants in patients with pulmonary tuberculosis.Semantic proximity Read ↗

A Familial Syndrome of Pulmonary Nontuberculous Mycobacteria InfectionsSemantic proximity Read ↗

Pulmonary Cryptococcosis in Apparently Immunocompetent Hosts: Host Susceptibility, Occult Immunodeficiency and Clinical Implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.