Article
The expression pattern of two zebrafish achaete-scute homolog (ash) genes is altered in the embryonic brain of the cyclops mutant.
Developmental biology - 1 Dec 1994
Allende M L, Weinberg E S
Abstract excerpt
Two achaete-scute homolog sequences, Zash-1a and Zash-1b, were isolated from a zebrafish embryonic cDNA library. The Zash-1a cDNA encodes a protein very similar to rat Mash-1 and Xenopus Xash-1, with over 94% identity in the C-terminal three-fourths of all three polypeptides. The Zash-1b cDNA encodes a more distantly related protein, with 80% identity of amino acids to Mash-1 in this part of the sequence. At 24...
Topics
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Transcription Factors
- Brain
- Cloning, Molecular
- DNA Primers
- DNA-Binding Proteins
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- In Situ Hybridization