Article
A discrete subpopulation of human monocytes expresses a neutrophil-like proinflammatory (P) phenotype.
The American journal of physiology - 1 Dec 1994
Owen C A, Campbell M A, Boukedes S S, Stockley R A, Campbell E J
Abstract excerpt
We have demonstrated that a discrete and naturally occurring subpopulation of human monocytes expresses a neutrophil-like proinflammatory (P) phenotype. P monocytes constitute 20-30% of the circulating monocyte pool and are characterized by 1) avid adherence to extracellular matrix through high-level cell-surface expression of alpha 5-, beta 1-, and beta 2-integrins; 2) high capacity to produce reactive oxygen...
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