Article
Monocrotophos pesticide modulates the expression of sexual differentiation genes and causes phenotypic feminization in zebrafish (Danio rerio).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Jan 2013
Zhang Xiaona, Gao Lei, Yang Kunfeng, Tian Hua, Wang Wei, Ru Shaoguo
Abstract excerpt
Monocrotophos (MCP) is an organophosphorus pesticide moderately toxic to fish, and it has significant estrogenic properties in vivo. In this study, zebrafish (Danio rerio) were exposed to 0.001, 0.010, and 0.100 mg/L 40% MCP pesticide in a semi-static manner from fertilization to 40 days post-hatching. Histological analyses were performed to determine whether sex differentiation in zebrafish was affected by MCP,...
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