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Article

Expression of Bruton's tyrosine kinase protein within the B cell lineage

1 Dec 1994

Abstract excerpt

Defects in the gene encoding Bruton's tyrosine kinase (Btk), normally expressed in B cells, cause X-linked agammaglobulinemia (XLA). The phenotype of XLA is characterized by a lack of circulating B cells and immunoglobulin. It has been suggested that B cell maturation from the pre-B cell stage to more mature stages is dependent on the appropriate expression of this gene. The Btk mRNA is expressed in B cells and...

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PMID: 7805739
DOI: 10.1002/eji.1830241228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of Bruton's tyrosine kinase protein within the B cell lineagePMID 7805739Read ↗

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