Article
Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men.
Circulation - 15 Jan 1995
Stengård J H, Zerba K E, Pekkanen J, Ehnholm C, Nissinen A, Sing C F
Abstract excerpt
BACKGROUND: There is ample evidence from cross-sectional studies of an association between allelic variation of the gene coding for apolipoprotein E (apoE) and interindividual variation in plasma lipids, and the presence of coronary heart disease (CHD). There have been no prospective studies, however, to evaluate the usefulness of allelic variation of the apoE gene for predicting CHD. METHODS AND RESULTS: Two...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoproteins E
- Blood Pressure
- Cohort Studies
- Coronary Disease
- Finland
- Follow-Up Studies
- Genotype
- Humans
- Longitudinal Studies
