Mechanisms of the combined effect of asbestos and smoking in the etiology of lung cancer.

Abstract excerpt

The joint effects of exposure to two known lung carcinogens, tobacco smoking and asbestos, are reviewed. The variable pattern of interaction--ranging from supramultiplicative to less than additive--may reflect the fact that both asbestos and smoking are complex carcinogens which can affect more than one stage of lung carcinogenesis. The joint effect of two such agents will depend on the relative magnitude of the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Air Quality and Health Impacts
• Share to Occupational and environmental lung diseases